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There are lots of reasons for people who are overweight or obese to lose weight. To be healthier. To look better. To feel better. To have more energy. No matter what the reason, successful weight loss and healthy weight management depend on sensible goals and expectations. If you set sensible goals for yourself, chances are you'll be more likely to meet them and have a better chance of keeping the weight off. In fact, losing even five to 10 percent of your weight is the kind of goal that can help improve your health.

Most overweight people should lose weight gradually. For safe and healthy weight loss, try not to exceed a rate of two pounds per week. Sometimes, people with serious health problems associated with obesity may have legitimate reasons for losing weight rapidly. If so, a physician's supervision is required. What you weigh is the result of several factors: how much and what kinds of food you eat whether your lifestyle includes regular physical activity whether you use food to respond to stress and other situations in your life your physiologic and genetic make-up your age and health status.

Other scientists believe it is a sensory desire that drives cravings, so that we eat until we satisfy our sense of pleasure from a particular food and then move to a different food that we sensorily desire. To support this theory, researchers have shown that people eating a multi-course meal may eat 60% more than people eating only one or two foods. Eating dessert is the natural outcome of choosing foods that satisfy our sweet appetite after satisfying hunger and savory foods during a meal. Hunger and appetite can be better managed by consciously eating a variety of food, staving off cravings between meals with nutritious filling snacks, and by drinking lots of water.

Successful weight loss and weight management should address all of these factors. And that's the reason to ignore products and programs that promise quick and easy results, or that promise permanent results without permanent changes in your lifestyle. Any ad that says you can lose weight without lowering the calories you take in and/or increasing your physical activity is selling fantasy and false hope. In fact, some people would call it fraud. Furthermore, the use of some products may not be safe.

Researchers on obesity are studying the biology of appetite to eventually develop new drugs or effective behavioral treatments for .Weight Loss.., a $30 billion industry. Current .Weight Loss.. plans are rarely successful in the long term, and can be dangerous. Doctors do not readily prescribe once- popular diet pills (amphetamines) because of their addictive properties and negative adrenaline-stimulating side effects. Newer drugs such as fenfluramine appear to be safe for long- term use and have proved effective for .Weight Loss.. by boosting the body's levels of serotonin (neurotransmitter that sends fullness signals to the brain). A recent study concluded fenfluramine can be taken indefinitely with minimal side effects and no apparent risk of addition.

Dexfenfluramine is a more effective form of the drug and is available in Europe but not in the U.S. Fluoxetine (Prozac), a prescription antidepressant, appears to promote .Weight Loss.. similar to fenfluramine and is being reviewed by the FDA for obesity treatment. Peptides such as neuropeptide Y and cholecystokinin seem to cause satiety, although initial studies show negative side effects and a diminished effectiveness with continued use. These drugs are designed to work on hunger, the physiological need for food. Appetite refers to the more social aspect of food choices. Biobehavioral health experts believe pleasure is the most important element of appetite, yet food cravings cannot be scientifically studied since they are extremely subjective and cannot be objectively measured. Behavioral scientists believe that abstinence can drive a craving and some believe that physiological needs create cravings (depressed people crave sweet foods because the carbohydrates boost serotonin, a mood-elevating neurotransmitter).

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